CHRONOTHERAPEUTIC DRUG DELIVERY SYSTEM PDF

It is often recommended to use Crestor in conjunction with a diet low in fats and cholesterol, and exercise about 30 min. Crestor is available as a generic termed Rosuvastatin or Rosuvastatin calcium. Side effects of Crestor include headache, depression, muscle aches or pains, joint pain, sleep problems insomnia or nightmares , constipation, nausea, stomach pain, indigestion, or diarrhea. The system released the drug rapidly after a certain lag time due to the rupture of the ethyl cellulose film. The lag time of the system could be modified by level of swelling layer and rupturable coating.

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It is often recommended to use Crestor in conjunction with a diet low in fats and cholesterol, and exercise about 30 min. Crestor is available as a generic termed Rosuvastatin or Rosuvastatin calcium.

Side effects of Crestor include headache, depression, muscle aches or pains, joint pain, sleep problems insomnia or nightmares , constipation, nausea, stomach pain, indigestion, or diarrhea. The system released the drug rapidly after a certain lag time due to the rupture of the ethyl cellulose film.

The lag time of the system could be modified by level of swelling layer and rupturable coating. Slide 1. Davis SS, Illum L. International Journal of Phar m ac e ut i c s ; : Gennaro A R , ed.

Re m i ngton. The Sci e nce and Pra c tice of Phar m acy 20th ed. Pulsat i le drug de l ivery s y st e m s Crit Rev. Therapeut i c Drug Car r ier Syste m s ; 1 8 5 5 8. P uls a tile dr u g delive r y s yst e m s using hydrog e ls. Advanced Drug Del i v e ry R ev i ews ;11 : 0 8. Kikuchi A, Okano T.

Pulsati l e d rug release con t rol u sing hydroge l s. Advanc e d Drug Del i v e ry Revi e ws ;54 : 53 -

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